Protein synthesis Animation – translation initiation in prokaryotes



Protein synthesis Animation – translation initiation in prokaryotes -This video animation lecture explains the prokaryotic protein synthesis initiation in animation form. Translation is a process whereby the base sequence of the messenger RNA is converted into the amino acid sequence of a polypeptide this process involves an mRNA tRNAs amino acids are ribosome and other accessory proteins and RNA consists of three main parts proportion from the five prime end to the translation start codon is the five prime untranslated leader region were simply called the leader the central portion is called the reading frame it commences with the start codon AUG followed by a series of three nucleotide codons each of which specifies an amino acid and it ends with one of the stop codons UAA Yu AG or UG a the final portion of the mRNA consists of the section from the stop codon to the three prime and carve the three prime untranslated trailer sequence were simply called the trailer mRNA is very in length because of differences in all three parts of this molecule) RNA functions to bring amino acids to the growing polypeptide during translation consists of a single RNA chain of about 75 to 90 nucleotides each tRNA having a different sequence of bases after it is transcribed the tRNA folds up into a characteristic cloverleaf structure the energy codon contains a three nucleotide sequence that is complementary to a codon on the mRNA the amino acid is attached to the three prime free and at the top of the cloverleaf ribosome assembles amino acids into a polypeptide ribosomes consist of two parts a large subunit and a small subunit ribosomal is made of ribosomal RNA in various proteins the active ribosome contains three tRNA binding sites namely exit PE to deal and a amino ACL in prokaryotes translation initiation occurs in three steps as follows first the small ribosomal subunit three is subunit complexes with three proteins named initiation factor why an initiation factor to and initiation factor three molecule of GTP also attaches the ribosome AIF GTP complex recognises a sequence in the leader of stream of the AUG start codon sequences called the ribosome binding site or the shine dog gonna sequence after its discoverer’s sequences complementary to a sequence of the three prime end of the 16 S ribosomal RNA of the 30 as ribosomal subunit and serves to align the ribosome on the mRNA in its proper reading frame sack and translation begins at the start codon AUG a few bases downstream of the ribosome binding site of the first AUG and proteins specifies a modified form of methionine this modification consists that the addition of a formyl group to methionine making it for new methionine; of this initiator tRNA containing as Matt complements AUG upon binding of asthma tRNA to mRNA three is released with the remaining assembled components called the 30 as initiation complex lastly the large ribosomal subunit 50 as subunit binds to the 30 as initiation complex GTP is hydrolysed and I have one and AIF to a released the final complexes called the 70 as initiation complex the map tRNA is now situated in the piece side of the ribosome with it and I: hydrogen bonded to the mRNA start codon initiation is now complete and elongation for.
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Protein synthesis Animation – translation initiation in prokaryotes
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